Fighting disease-causing bacteria is part of human history. Now humanity is in danger of losing the battle again. Since more and more bacteria are becoming resistant to antibiotics, there are too few new agents. BILD explains the biggest medical threat in decades and what we can do about it. President of the Paul Ehrlich Society for Infection Therapy, Mathias Pletz, warned this week that the effectiveness of antibiotics is increasingly threatened.

Pletz literally: "We are currently in the process of losing the achievements of modern medicine and returning to the time before the discovery of penicillin."

Professor Yvonne Mast holds two ampoules filled with bacteria in her hands in the cold storage room of the German Collection of Microorganisms and Cell Cultures 

Is medicine really that bad?

Yes, says microbiologist prof. Yvonne Mast, who is on The Leibniz Institute DSMZ (German Collection of Microorganisms and Cell Cultures) researches: “Antibiotics were the greatest medical achievement ever. The fact that more and more resistance is emerging now and that there is a lack of new antibiotics is a big threat."

The numbers speak for themselves

A recent study calculated that more than 39 million people worldwide could die from infections with antibiotic-resistant germs by 2050! I: In the European Union alone, 35,000 people die annually from infections caused by resistant pathogens.

Why is there so much resistance?

Intensive care doctor prof. Frank M. Brunkhorst (Jena University Hospital) for BILD: "There are two main reasons: First, too many antibiotics are still prescribed, especially in outpatient settings. Second: due to international travel, which is on the rise again after Corona, many resistant bacteria are coming to us. Resistance rates are extremely high, especially in countries such as Greece, Portugal, Turkey, but also in India and other Asian countries.

We have to warn people here: if someone brings such a germ from vacation and infects a sick grandfather, it can be life-threatening."

Why no meat: the creation of antibiotic resistance in animal husbandry

In which cases are antibiotics often not needed? For almost all respiratory infections. They are usually caused by viruses against which antibiotics can do nothing. Especially children with a cold they are given too much medicine. And also for urinary tract infections such as: B. Cystitis, antibiotics are still prescribed too careless; often they are not even necessary.

Why are there not enough new antibiotics?
As of 2017, only twelve new antibiotics have been approved. Prof. Yvonne Mast: "The journey from the discovery of matter to application is long and expensive. Clinical studies in particular are expensive. Only one out of about 5,000 substances reaches market maturity, the development period is 8 to 15 years, and the development costs are between 100 million and 2 billion euros. Due to the unfavorable cost-benefit ratio, industry is increasingly withdrawing from antibiotic research and development programs.
The profit from investing in antibiotics is significantly lower than in other drugs."
Transfers: Bild
https://www.bild.de/leben-wissen/medizin/kampf-gegen-antibiotika-resistenzen-menschheit-droht-rueckschlag-671127ec1eb02276e252d63d

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