The liver must metabolize and disable everything that increases ammonia in the body. The main culprit for this is food of animal origin. When food of animal origin is digested, it creates ammonia (alkaline gas), which your intestines absorb into the blood, so that the liver can turn it into urine, which will be expelled by your kidneys. Americans (given that they are the largest consumers of animal food on the planet per person), are in first place for creating excess ammonia in the intestines, which weakens the liver and causes hepatic coma or paralysis. Foods that contain ammonia (in addition to meat, eggs, and milk) are drugs, such as sedatives, tranquilizers, anesthetics, analgesics (pain relievers), and diuretics. For years, I have seen patients with liver damage in my clinic, and even and with acute congestion that causes hepatic coma worse than alcohol, drugs, and poisons. This is caused by a high-protein diet. These diets come and go, and currently the Zone and Atkinson diets are in fashion. These diets (like any diet) can cause weight loss, but they can also increase the amount of ammonia and paralyze the liver. It's a double burden, because the liver can't process all this extra cholesterol you're ingesting in huge amounts.
And that alone can cause a heart attack. You're guaranteed to be slim in a hospital bed or coffin, but it's better to have a healthy liver than to be sick or dead.
You can watch the interview with Arnold Schwarzenegger at:
https://vimeo.com/360881982